Excessive daytime sleepiness in de novo and treated Parkinson's disease
Identifieur interne : 002877 ( Main/Corpus ); précédent : 002876; suivant : 002878Excessive daytime sleepiness in de novo and treated Parkinson's disease
Auteurs : Giovanni Fabbrini ; Piero Barbanti ; Cinzia Aurilia ; Nicola Vanacore ; Caterina Pauletti ; Giuseppe MecoSource :
- Movement Disorders [ 0885-3185 ] ; 2002-09.
English descriptors
Abstract
Excessive daytime sleepiness (EDS) in Parkinson's disease (PD) is due to either treatment‐related factors or the disease itself. The study of this disturbing phenomenon in de novo parkinsonian patients may contribute to a better understanding of its pathophysiology. We conducted a case control study in which we compared 25 PD patients who had never been treated before with dopaminergic drugs (de novo PD), 50 PD patients being treated with dopaminergic drugs (treated PD), and 25 healthy control subjects, all of whom were matched for age and gender. EDS was measured by means of the Epworth Sleepiness Scale (ESS) and quality of sleep by means of the Pittsburgh Sleep Quality Index (PSQI). ESS and PSQI scores were not statistically different between de novo PD patients and controls, whereas they were significantly higher in treated PD. Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered. © 2002 Movement Disorder Society
Url:
DOI: 10.1002/mds.10193
Links to Exploration step
ISTEX:3267D89F66EB1B72407897E7F7519334C4CB562BLe document en format XML
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The study of this disturbing phenomenon in de novo parkinsonian patients may contribute to a better understanding of its pathophysiology. We conducted a case control study in which we compared 25 PD patients who had never been treated before with dopaminergic drugs (de novo PD), 50 PD patients being treated with dopaminergic drugs (treated PD), and 25 healthy control subjects, all of whom were matched for age and gender. EDS was measured by means of the Epworth Sleepiness Scale (ESS) and quality of sleep by means of the Pittsburgh Sleep Quality Index (PSQI). ESS and PSQI scores were not statistically different between de novo PD patients and controls, whereas they were significantly higher in treated PD. Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered. © 2002 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Excessive daytime sleepiness in de novo and treated Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Sleepiness in Parkinson's Disease</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Excessive daytime sleepiness in de novo and treated Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Giovanni</namePart><namePart type="family">Fabbrini</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><description>Correspondence: Department of Neurological Sciences, University La Sapienza, Viale del'Università 30, 00185 Rome, Italy</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Piero</namePart><namePart type="family">Barbanti</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cinzia</namePart><namePart type="family">Aurilia</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Nicola</namePart><namePart type="family">Vanacore</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Caterina</namePart><namePart type="family">Pauletti</namePart><namePart type="termsOfAddress">MS</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Giuseppe</namePart><namePart type="family">Meco</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurological Sciences, University La Sapienza, Rome, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2002-09</dateIssued><dateCaptured encoding="w3cdtf">2001-08-14</dateCaptured><dateValid encoding="w3cdtf">2002-01-11</dateValid><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">4</extent><extent unit="references">29</extent><extent unit="words">2921</extent></physicalDescription><abstract lang="en">Excessive daytime sleepiness (EDS) in Parkinson's disease (PD) is due to either treatment‐related factors or the disease itself. The study of this disturbing phenomenon in de novo parkinsonian patients may contribute to a better understanding of its pathophysiology. We conducted a case control study in which we compared 25 PD patients who had never been treated before with dopaminergic drugs (de novo PD), 50 PD patients being treated with dopaminergic drugs (treated PD), and 25 healthy control subjects, all of whom were matched for age and gender. EDS was measured by means of the Epworth Sleepiness Scale (ESS) and quality of sleep by means of the Pittsburgh Sleep Quality Index (PSQI). ESS and PSQI scores were not statistically different between de novo PD patients and controls, whereas they were significantly higher in treated PD. Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered. © 2002 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>sleep</topic><topic>excessive daytime sleepiness</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title><subTitle>Official Journal of the Movement Disorder Society</subTitle></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Brief Reports</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><detail type="issue"><caption>no.</caption><number>5</number></detail><extent unit="pages"><start>1026</start><end>1030</end><total>5</total></extent></part></relatedItem><identifier type="istex">3267D89F66EB1B72407897E7F7519334C4CB562B</identifier><identifier type="DOI">10.1002/mds.10193</identifier><identifier type="ArticleID">MDS10193</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2002 Movement Disorders Society</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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